domingo, 1 de marzo de 2015

Rules and Guidance for Pharmaceutical Manufacturers Distributors 2015 - The Green Guide


Rules and Guidance for Pharmaceutical Manufacturers Distributors 2015 - The Green Guide
Author: MHRA (Medicines and Healthcare products Regulatory Agency)
Publisher: Pharmaceutical Press
Published: 2015
Hardback, 1 volume
Pages: 232 pp.
Product Dimensions: 244 x 172mm

This is the ninth edition of Rules and Guidance for Pharmaceutical Manufacturers and Distributors, compiled by MHRA. Commonly known as the Green Guide, it remains an essential reference for all manufacturers and distributors of medicines in Europe. It provides a single authoritative source of European and UK guidance, information and legislation relating to the manufacture and distribution of human medicines.
The Green Guide reproduces all the elements of the new Rules and Guidance for Pharmaceutical Manufacturers and Distributors 2015 (the Orange Guide) that are relevant to distributors. So if you’re involved in the wholesale supply, distribution and brokering of medicines for human use and the distribution of active substances, this is the one-stop guide you need.

This 2015 edition has been updated to incorporate the revised EU Guidelines on Good Distribution Practice. In addition, it includes new sections on:
§  GDP Quality Systems
§  The Gold Standard for Responsible Persons
§  MHRA Innovation Office
§  The Application and Inspection process – 'what to expect'
§  List of persons who can be supplied with medicines by way of wholesale dealing (Human Medicines Regulations 2012)
§  EU Commission Q&A on GDP guidelines
§  Controls on certain medicinal products
§  Compliance Management and Inspection Action Group
§  Handling returns of non-defective medicinal products
§  Risk-based inspection programme
§  Product recall/withdrawal – testing the recall process
§  Short term storage of ambient and refrigerated medicinal products – requirements for a Wholesale Dealers Authorisation (WDA)

The work also includes a new flow chart on registration requirements for UK companies involved in the sourcing and supply of active substances (ASs) to be used in the manufacture of licensed human medicines.
The Green Guide is compiled by the Inspection, Enforcement and Standards Division, MHRA, London, UK. Building on the restructured contents and fresh design of the last edition, it’s easier than ever to find the answers you need.


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