PCPC 2014 Safety Evaluation Guidelines (PDF
Download) - Personal Care Products Council
The Personal Care Products Council Safety
Evaluation Guidelines provide manufacturers of cosmetic, toiletry and fragrance
products with guidance in the use of pre-clinical and clinical safety testing
as a means to substantiate the safety of both ingredients and finished cosmetic
products.
Table
of Contents
1.
Introduction
2.
Overview of the Safety Evaluation Guidelines
3.
Evaluation of Primary Dermal Irritation Potential
4.
Evaluation of Eye Irritation Potential
5.
Evaluation of Mucous Membrane Irritation Potential
6.
Evaluation of Dermal Sensitization Potential
7.
Evaluation of Photoirritation and Photoallergy Potential
8.
Safety-in-Use Studies in Humans
9.
Evaluation of Dermal Toxicity Potential
10.
Evaluation of Oral Toxicity Potential
11. Evaluation
of Inhalation Toxicity Potential
12.
Evaluation of Reproductive and Developmental Toxicity Potential
13.
Evaluation of Genotoxicity Potential
14.
Evaluation of Skin Absorption Potential
15.
Computational Toxicology
16.
Evaluation of Botanical Safety
17.
Glossary
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